Fare Guide

Estimated lowest fares found within 7 days

Cheapest Airline Avianca

The cheapest airline(s) flying from Santiago to Santo Domingo is Avianca.

  • Avianca Avianca
  • Copa Airlines Copa Airlines
  • Arajet Arajet
  • JetSmart JetSmart
  • LATAM Airlines Group SA LATAM Airlines Group SA
  • American Airlines American Airlines
Cheapest Month May

Travel Period: December 2024 - November 2025

The cheapest month(s) to fly from Santiago to Santo Domingo is May.

  • Dec 2024
  • Jan 2025
  • Feb 2025
  • Mar 2025
  • Apr 2025
  • May 2025
  • Jun 2025
  • Jul 2025
  • Aug 2025
  • Sep 2025
  • Oct 2025
  • Nov 2025
Cheapest Day of the Week Wednesday

The cheapest day(s) of the week to fly from Santiago to Santo Domingo is Wednesday.

  • Sun Sunday
  • Mon Monday
  • Tue Tuesday
  • Wed Wednesday
  • Thu Thursday
  • Fri Friday
  • Sat Saturday

Flight Schedules

Last Updated: Sat, 2 Nov, 2024

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  • Availability
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  • 22:30 SCL
    12:12 SDQ
    14Hrs, 42m 1 Stop (MIA)
  • SCLSantiago Arturo Merino Benitez Airport 22:30 - SDQ 12:12 14h 42m 1 Stop (MIA) Miami
  • SCLSantiago Arturo Merino Benitez Airport 22:30
    MIAMiami International Airport 08:57
  • MIAMiami International Airport 05:10
    SDQSanto Domingo Las Americas Airport 12:12
  • 14h 42m (3h 47m)
  • 1 Stop MIA · Miami 3h 47m
  • American Airlines (AA 912)Boeing 777 200
    American Airlines (AA 2099)Boeing 737 800
  • American Airlines (AA 912)
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    • -
    • -
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    • -
    • -
    • -
  • 22:30 SCL
    12:10 SDQ
    14Hrs, 40m 1 Stop (MIA)
  • SCLSantiago Arturo Merino Benitez Airport 22:30 - SDQ 12:10 14h 40m 1 Stop (MIA) Miami
  • SCLSantiago Arturo Merino Benitez Airport 22:30
    MIAMiami International Airport 08:55
  • MIAMiami International Airport 05:10
    SDQSanto Domingo Las Americas Airport 12:10
  • 14h 40m (3h 45m)
  • 1 Stop MIA · Miami 3h 45m
  • American Airlines (AA 912)Boeing 777 200
    American Airlines (AA 2099)Boeing 737 800
  • American Airlines (AA 912)
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    • -
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    • S
  • 00:45 SCL
    10:55 SDQ
    11Hrs, 10m 1 Stop (BOG)
  • SCLSantiago Arturo Merino Benitez Airport 00:45 - SDQ 10:55 11h 10m 1 Stop (BOG) Bogota
  • SCLSantiago Arturo Merino Benitez Airport 00:45
    BOGBogota Airport 07:15
  • BOGBogota Airport 04:55
    SDQSanto Domingo Las Americas Airport 10:55
  • 11h 10m (2h 20m)
  • 1 Stop BOG · Bogota 2h 20m
  • Avianca (AV 240)Airbus A320 Neo
    Avianca (AV 208)Airbus A320 Neo
  • Avianca (AV 240)
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    • T
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    • -
  • 01:11 SCL
    10:49 SDQ
    10Hrs, 38m 1 Stop (PTY)
  • SCLSantiago Arturo Merino Benitez Airport 01:11 - SDQ 10:49 10h 38m 1 Stop (PTY) Panama City
  • SCLSantiago Arturo Merino Benitez Airport 01:11
    PTYPanama City Tocumen International Airport 07:18
  • PTYPanama City Tocumen International Airport 06:04
    SDQSanto Domingo Las Americas Airport 10:49
  • 10h 38m (1h 14m)
  • 1 Stop PTY · Panama City 1h 14m
  • Copa Airlines (CM 118)Boeing 737 800
    Copa Airlines (CM 463)Boeing 737 800
  • Copa Airlines (CM 118)
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    • -
    • -
  • 01:11 SCL
    13:08 SDQ
    12Hrs, 57m 1 Stop (PTY)
  • SCLSantiago Arturo Merino Benitez Airport 01:11 - SDQ 13:08 12h 57m 1 Stop (PTY) Panama City
  • SCLSantiago Arturo Merino Benitez Airport 01:11
    PTYPanama City Tocumen International Airport 09:37
  • PTYPanama City Tocumen International Airport 06:04
    SDQSanto Domingo Las Americas Airport 13:08
  • 12h 57m (3h 33m)
  • 1 Stop PTY · Panama City 3h 33m
  • Copa Airlines (CM 118)Boeing 737 800
    Copa Airlines (CM 298)Boeing 737 800
  • Copa Airlines (CM 118)
    • M
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  • 01:12 SCL
    10:49 SDQ
    10Hrs, 37m 1 Stop (PTY)
  • SCLSantiago Arturo Merino Benitez Airport 01:12 - SDQ 10:49 10h 37m 1 Stop (PTY) Panama City
  • SCLSantiago Arturo Merino Benitez Airport 01:12
    PTYPanama City Tocumen International Airport 07:18
  • PTYPanama City Tocumen International Airport 06:05
    SDQSanto Domingo Las Americas Airport 10:49
  • 10h 37m (1h 13m)
  • 1 Stop PTY · Panama City 1h 13m
  • Copa Airlines (CM 118)Boeing 737 800
    Copa Airlines (CM 463)Boeing 737 800
  • Copa Airlines (CM 118)
    • -
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    • S
  • 01:12 SCL
    13:08 SDQ
    12Hrs, 56m 1 Stop (PTY)
  • SCLSantiago Arturo Merino Benitez Airport 01:12 - SDQ 13:08 12h 56m 1 Stop (PTY) Panama City
  • SCLSantiago Arturo Merino Benitez Airport 01:12
    PTYPanama City Tocumen International Airport 09:37
  • PTYPanama City Tocumen International Airport 06:05
    SDQSanto Domingo Las Americas Airport 13:08
  • 12h 56m (3h 32m)
  • 1 Stop PTY · Panama City 3h 32m
  • Copa Airlines (CM 118)Boeing 737 800
    Copa Airlines (CM 298)Boeing 737 800
  • Copa Airlines (CM 118)
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • 01:21 SCL
    10:49 SDQ
    10Hrs, 28m 1 Stop (PTY)
  • SCLSantiago Arturo Merino Benitez Airport 01:21 - SDQ 10:49 10h 28m 1 Stop (PTY) Panama City
  • SCLSantiago Arturo Merino Benitez Airport 01:21
    PTYPanama City Tocumen International Airport 07:18
  • PTYPanama City Tocumen International Airport 06:20
    SDQSanto Domingo Las Americas Airport 10:49
  • 10h 28m (58m)
  • 1 Stop PTY · Panama City 58m
  • Copa Airlines (CM 276)Boeing 737 800
    Copa Airlines (CM 463)Boeing 737 800
  • Copa Airlines (CM 276)
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  • 01:21 SCL
    13:08 SDQ
    12Hrs, 47m 1 Stop (PTY)
  • SCLSantiago Arturo Merino Benitez Airport 01:21 - SDQ 13:08 12h 47m 1 Stop (PTY) Panama City
  • SCLSantiago Arturo Merino Benitez Airport 01:21
    PTYPanama City Tocumen International Airport 09:37
  • PTYPanama City Tocumen International Airport 06:20
    SDQSanto Domingo Las Americas Airport 13:08
  • 12h 47m (3h 17m)
  • 1 Stop PTY · Panama City 3h 17m
  • Copa Airlines (CM 276)Boeing 737 800
    Copa Airlines (CM 298)Boeing 737 800
  • Copa Airlines (CM 276)
    • -
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    • -
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    • -
  • 01:21 SCL
    13:08 SDQ
    12Hrs, 47m 1 Stop (PTY)
  • SCLSantiago Arturo Merino Benitez Airport 01:21 - SDQ 13:08 12h 47m 1 Stop (PTY) Panama City
  • SCLSantiago Arturo Merino Benitez Airport 01:21
    PTYPanama City Tocumen International Airport 09:37
  • PTYPanama City Tocumen International Airport 06:20
    SDQSanto Domingo Las Americas Airport 13:08
  • 12h 47m (3h 17m)
  • 1 Stop PTY · Panama City 3h 17m
  • Copa Airlines (CM 276)Boeing 737 800
    Copa Airlines (CM 298)Boeing 737 Max 9 Passenger
  • Copa Airlines (CM 276)
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    • -
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    • -
    • -
    • -
    • -
  • 03:23 SCL
    13:08 SDQ
    10Hrs, 45m 1 Stop (PTY)
  • SCLSantiago Arturo Merino Benitez Airport 03:23 - SDQ 13:08 10h 45m 1 Stop (PTY) Panama City
  • SCLSantiago Arturo Merino Benitez Airport 03:23
    PTYPanama City Tocumen International Airport 09:37
  • PTYPanama City Tocumen International Airport 08:16
    SDQSanto Domingo Las Americas Airport 13:08
  • 10h 45m (1h 21m)
  • 1 Stop PTY · Panama City 1h 21m
  • Copa Airlines (CM 475)Boeing 737 Max 9 Passenger
    Copa Airlines (CM 298)Boeing 737 800
  • Copa Airlines (CM 475)
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    • S
  • 03:23 SCL
    16:23 SDQ
    14Hrs, 00m 1 Stop (PTY)
  • SCLSantiago Arturo Merino Benitez Airport 03:23 - SDQ 16:23 14h 1 Stop (PTY) Panama City
  • SCLSantiago Arturo Merino Benitez Airport 03:23
    PTYPanama City Tocumen International Airport 12:52
  • PTYPanama City Tocumen International Airport 08:16
    SDQSanto Domingo Las Americas Airport 16:23
  • 14h (4h 36m)
  • 1 Stop PTY · Panama City 4h 36m
  • Copa Airlines (CM 475)Boeing 737 Max 9 Passenger
    Copa Airlines (CM 128)Boeing 737 800
  • Copa Airlines (CM 475)
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  • 03:23 SCL
    16:23 SDQ
    14Hrs, 00m 1 Stop (PTY)
  • SCLSantiago Arturo Merino Benitez Airport 03:23 - SDQ 16:23 14h 1 Stop (PTY) Panama City
  • SCLSantiago Arturo Merino Benitez Airport 03:23
    PTYPanama City Tocumen International Airport 12:52
  • PTYPanama City Tocumen International Airport 08:16
    SDQSanto Domingo Las Americas Airport 16:23
  • 14h (4h 36m)
  • 1 Stop PTY · Panama City 4h 36m
  • Copa Airlines (CM 475)Boeing 737 Max 9 Passenger
    Copa Airlines (CM 128)Boeing 737 700
  • Copa Airlines (CM 475)
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  • 03:23 SCL
    13:08 SDQ
    10Hrs, 45m 1 Stop (PTY)
  • SCLSantiago Arturo Merino Benitez Airport 03:23 - SDQ 13:08 10h 45m 1 Stop (PTY) Panama City
  • SCLSantiago Arturo Merino Benitez Airport 03:23
    PTYPanama City Tocumen International Airport 09:37
  • PTYPanama City Tocumen International Airport 08:16
    SDQSanto Domingo Las Americas Airport 13:08
  • 10h 45m (1h 21m)
  • 1 Stop PTY · Panama City 1h 21m
  • Copa Airlines (CM 475)Boeing 737 Max 9 Passenger
    Copa Airlines (CM 298)Boeing 737 Max 9 Passenger
  • Copa Airlines (CM 475)
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  • 05:14 SCL
    16:23 SDQ
    12Hrs, 09m 1 Stop (PTY)
  • SCLSantiago Arturo Merino Benitez Airport 05:14 - SDQ 16:23 12h 09m 1 Stop (PTY) Panama City
  • SCLSantiago Arturo Merino Benitez Airport 05:14
    PTYPanama City Tocumen International Airport 12:52
  • PTYPanama City Tocumen International Airport 10:07
    SDQSanto Domingo Las Americas Airport 16:23
  • 12h 09m (2h 45m)
  • 1 Stop PTY · Panama City 2h 45m
  • Copa Airlines (CM 174)Boeing 737 800
    Copa Airlines (CM 128)Boeing 737 800
  • Copa Airlines (CM 174)
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 05:24 SCL
    16:23 SDQ
    11Hrs, 59m 1 Stop (PTY)
  • SCLSantiago Arturo Merino Benitez Airport 05:24 - SDQ 16:23 11h 59m 1 Stop (PTY) Panama City
  • SCLSantiago Arturo Merino Benitez Airport 05:24
    PTYPanama City Tocumen International Airport 12:52
  • PTYPanama City Tocumen International Airport 10:17
    SDQSanto Domingo Las Americas Airport 16:23
  • 11h 59m (2h 35m)
  • 1 Stop PTY · Panama City 2h 35m
  • Copa Airlines (CM 396)Boeing 737 800
    Copa Airlines (CM 128)Boeing 737 800
  • Copa Airlines (CM 396)
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    • -
  • 05:24 SCL
    16:23 SDQ
    11Hrs, 59m 1 Stop (PTY)
  • SCLSantiago Arturo Merino Benitez Airport 05:24 - SDQ 16:23 11h 59m 1 Stop (PTY) Panama City
  • SCLSantiago Arturo Merino Benitez Airport 05:24
    PTYPanama City Tocumen International Airport 12:52
  • PTYPanama City Tocumen International Airport 10:17
    SDQSanto Domingo Las Americas Airport 16:23
  • 11h 59m (2h 35m)
  • 1 Stop PTY · Panama City 2h 35m
  • Copa Airlines (CM 396)Boeing 737 800
    Copa Airlines (CM 128)Boeing 737 700
  • Copa Airlines (CM 396)
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  • 06:35 SCL
    17:20 SDQ
    11Hrs, 45m 1 Stop (BOG)
  • SCLSantiago Arturo Merino Benitez Airport 06:35 - SDQ 17:20 11h 45m 1 Stop (BOG) Bogota
  • SCLSantiago Arturo Merino Benitez Airport 06:35
    BOGBogota Airport 13:35
  • BOGBogota Airport 10:45
    SDQSanto Domingo Las Americas Airport 17:20
  • 11h 45m (2h 50m)
  • 1 Stop BOG · Bogota 2h 50m
  • Avianca (AV 98)Airbus A320 Neo
    Avianca (AV 250)Airbus
  • Avianca (AV 98)
    • -
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  • 06:55 SCL
    17:20 SDQ
    11Hrs, 25m 1 Stop (BOG)
  • SCLSantiago Arturo Merino Benitez Airport 06:55 - SDQ 17:20 11h 25m 1 Stop (BOG) Bogota
  • SCLSantiago Arturo Merino Benitez Airport 06:55
    BOGBogota Airport 13:35
  • BOGBogota Airport 10:45
    SDQSanto Domingo Las Americas Airport 17:20
  • 11h 25m (2h 50m)
  • 1 Stop BOG · Bogota 2h 50m
  • Avianca (AV 98)Boeing 787 8
    Avianca (AV 250)Airbus
  • Avianca (AV 98)
    • -
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    • -
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    • -
  • 12:19 SCL
    22:07 SDQ
    10Hrs, 48m 1 Stop (PTY)
  • SCLSantiago Arturo Merino Benitez Airport 12:19 - SDQ 22:07 10h 48m 1 Stop (PTY) Panama City
  • SCLSantiago Arturo Merino Benitez Airport 12:19
    PTYPanama City Tocumen International Airport 18:36
  • PTYPanama City Tocumen International Airport 17:12
    SDQSanto Domingo Las Americas Airport 22:07
  • 10h 48m (1h 24m)
  • 1 Stop PTY · Panama City 1h 24m
  • Copa Airlines (CM 498)Boeing 737 Max 9 Passenger
    Copa Airlines (CM 268)Boeing 737 800
  • Copa Airlines (CM 498)
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    • S
  • 12:19 SCL
    01:44 SDQ
    14Hrs, 25m 1 Stop (PTY)
  • SCLSantiago Arturo Merino Benitez Airport 12:19 - SDQ 01:44 14h 25m 1 Stop (PTY) Panama City
  • SCLSantiago Arturo Merino Benitez Airport 12:19
    PTYPanama City Tocumen International Airport 22:13
  • PTYPanama City Tocumen International Airport 17:12
    SDQSanto Domingo Las Americas Airport 01:44
  • 14h 25m (5h 01m)
  • 1 Stop PTY · Panama City 5h 01m
  • Copa Airlines (CM 498)Boeing 737 Max 9 Passenger
    Copa Airlines (CM 107)Boeing 737 800
  • Copa Airlines (CM 498)
    • -
    • -
    • -
    • -
    • F
    • -
    • -
  • 12:19 SCL
    01:44 SDQ
    14Hrs, 25m 1 Stop (PTY)
  • SCLSantiago Arturo Merino Benitez Airport 12:19 - SDQ 01:44 14h 25m 1 Stop (PTY) Panama City
  • SCLSantiago Arturo Merino Benitez Airport 12:19
    PTYPanama City Tocumen International Airport 22:13
  • PTYPanama City Tocumen International Airport 17:12
    SDQSanto Domingo Las Americas Airport 01:44
  • 14h 25m (5h 01m)
  • 1 Stop PTY · Panama City 5h 01m
  • Copa Airlines (CM 498)Boeing 737 Max 9 Passenger
    Copa Airlines (CM 107)Boeing 737 700
  • Copa Airlines (CM 498)
    • M
    • T
    • W
    • T
    • -
    • S
    • S
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What’s the most popular airline flying from Santiago to Santo Domingo?

The most popular airline flying from Santiago to Santo Domingo is Copa Airlines. Find the latest flight deals on Wego.

How far is Santo Domingo from Santiago?

The flight distance between Santiago and Santo Domingo is 5775km. Check all available flights on Wego.

When is the earliest and latest flight of the day?

The earliest flight of the day departs at 00:45. The last flight of the day departs at 22:30. See the full list of flight times on Wego.